Miss Chambers of Little Rock was elected in 1922 at the same time as Frances Hunt of Pine Bluff. But because members were sworn in based on their last names, she was actually sworn in first.
She had trained as an attorney at both the University of Arkansas and the University of Chicago, but never practiced law. She served as Pulaski County probation officer from 1913 until 1917. At that time, she went to work for the Tuberculosis Association, where she would work until her death in 1941.
Miss Chambers served in the Arkansas General Assembly from 1923 until 1926.